The set point between an adaptive response to enzyme induction and a response that ultimately leads to cancer has no universal parameters, as it is influenced by differential species susceptibility, the dose and duration of xenobiotic exposure, and the age and sex of the exposed species or strain, and whether or not the xenobiotic is also mitogenic
Jelovac N, et al
Intensive lowering of low-density lipoprotein cholesterol levels for primary prevention of coronary artery disease
If you opt for smaller, multiple daily doses (e.g., 2 250 mcg), each injection is ~0.15 mL (~15 units)
10.9758/cpn.2015.13.1.62 87 SimM.BlekkenhorstL
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