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Experiments on cell proliferation have demonstrated that straight incubation of adipocytes with MG leads to enhanced cell proliferation [120], suggesting the potential involvement of MG in the development of adipose tissue in obesity (Figure 4)

J Appl Physiol 54 : 147151

This finding was first well established in women who are heterozygous for hypoxanthine phosphoribosyltransferase deficiency, and it has also been observed in several women heterozygous for severely deficient G6PD variants

Due to its white crystalline solid form, it can also be an abrasive (exfoliator)

Two case reports and literature review

This failure mainly leads to increased production of ROS, which can damage mitochondrial components (44)