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Although many of the symptoms improve with treatment, some problems caused by the condition can be irreversible if left untreated, warns the NHS

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This could help avoid interactions with medications or treatment approaches

But that peripheral-only action means it does not suppress appetite, does not change energy expenditure through central pathways, and does not produce the dramatic caloric deficits that GLP-1 agonists like semaglutide or tirzepatide create