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Winterbourn CC, and Hampton MB

designed a US-triggered MnWO X nanosystem modified with PEG (termed MnWO X -PEG) to endow the capability of GSH-enhanced ROS ( 1 O 2 and OH) production for killing malignant tumors (Figure 6D) ( X -PEG exhibited significantly time-dependent GSH consumption capacity through reducing W 6+ to W 5+ (Figure 6E), cooperating with increased ROS to achieve a powerful inhibition effect on tumors (Figure 6F)

& Lemire, B

doi: 10.1007/s40279-021-01502-0

These activities of GPx2 have been reported in metastatic cervical cancer through activation of the Wnt pathway (Wang et al

Liq., 2024, 399, 124388 CrossRef CAS