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The following equations were used to calculate beta cell function and insulin resistance: HOMA- = 20 fasting plasma insulin (U/ml)/[fasting plasma glucose (mmol/L) - 3.5], HOMA-IR = [Fasting plasma insulin (U/ml) Fasting plasma glucose (mmol/L)]/22.5

Rheumatol Int

Self-renewal of human embryonic stem cells requires insulin-like growth factor-1 receptor and ERBB2 receptor signaling

Multiple nanoemulsions

Native rhIGF-1 (mecasermin, brand name Increlex) is FDA-approved only for the long-term treatment of growth failure in pediatric patients with severe primary IGF-1 deficiency or with GH gene deletion who have developed neutralizing antibodies to GH