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2020 Apr 28;14(4):4890-4904

These findings reveal neuroprotection of lapatinib against Glu-induced neuronal death

Thus, astrocytes respond to -amyloid proteotoxic stress by undergoing plastic changes in both morphology and gene expression to clear -amyloid oligomers through phagocytic autophagy 585

Clinical trials of Bapineuzumab are mixed, with some Bapineuzumab studies suggesting mild cognition improvements and others suggesting little efficacy in slowing disease progression