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TERT promoter mutation Mutations in the promoter region of the TERT gene have emerged as key molecular alterations in gliomas, influencing tumor progression, prognosis, and treatment response

Gatidis S, Zelenak C, Fajol A, Lang E, Jilani K, Michael D, et al

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However, with aging, the GSH pool decreases and oxidized GSH (GSSG) may attack protein thiols and formed PSSG

The formation of macrophage foam cells is a characteristic and an early onset of atherosclerosis (Yang et al., 2017)