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10.1199/tab.0131 38 DixonD

The research methodologies typically employed in oncology pharmacologyincluding efficacy assays, omics predictions, target verification, and drug modificationculminate in integrating the unique characteristics of these compounds with advanced DDS to optimize clinical application

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The targeted formulation simultaneously suppresses MDR1 and BCL-2 expression at mRNA levels, overcoming inherent chemoresistance while maintaining negligible systemic toxicity as evidenced by stable murine body weights throughout treatment [230]

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