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Mitochondrial pyruvate carrier 1 expression controls cancer epithelial-mesenchymal transition and radioresistance

doi: 10.1097/hm9.0000000000000125

For example, ONP-302 treatment led to a marked reduction in Cxcl1 expression by CAFs that promote PMN-MDSC infiltration into the TME in line with our observation of reduced PMN-MDSCs in the LLC TME after ONP-302 treatment [50]