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Pilipenko V, Narbute K, Pupure J, Langrate IK, Muceniece R, Klua V

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The enzyme uses either iron or manganese as a cofactor and catalyzes the degradation or reduction of hydrogen peroxide (H2O2) to water and molecular oxygen, consequently completing the detoxification process imitated by SOD.35, 36 It is abundant in cells, where it continuously scouts for hydrogen peroxide molecules

This targeted, or regioselective, activation of IL-2 may help explain the broader improvements in neuroimmune integration and stress resilience observed in older biological systems