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For Group 2 DEGs (WT-unique genes), the analysis did not identify any specific pathways

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This is why some practitioners prefer it not just for multi-dose use but specifically because it's designed to remain chemically stable in a vial over an extended period

Mutations in LOXs genes in human epidermis have also been identified as the second most common cause of autosomal recessive congenital ichthyosis, while disruptions at the level of LOXs genes in mice led to the death of newborns owing to severely impaired skin barrier function [114, 130]