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Janus kinase (JAK) inhibitors represent newer targeted synthetic DMARDs with demonstrated efficacy, though they carry boxed warnings regarding serious infections, malignancy, major adverse cardiovascular events, and thrombosis

S100A12 can translocate from the cytosol to the membrane upon calcium activation

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Right after the session, the client can expect a light glow on their skin

As discussed above, astrocytes are clearly capable of synthetizing and using glutamine, and, although they undoubtedly supply glutamine to the neurons, these cells also contribute to meeting the physiological need of metabolizing this compound (Yudkoff et al., 1988)