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Despite increased expression of complex I and IV proteins with B12 supplementation and previously observed increased complex I and IV OCR in B12-supplemented, aged male mice [26], we did not observe an improvement in mitochondrial complex activity (i.e., oxygen consumption rate) in the aged female mice

A pharmaceutical preparation called Deltaran became available in some countries, combining DSIP with glycine for enhanced stability and effect

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( Under the proposed financial methodology, accounting for the impact of improper payments on expenditures could increase or decrease an ACO's amount of shared savings or shared losses

Second, as all analyses were exploratory, and the primary analysis for each endpoint was specified, multiple comparisons were performed only without P value correction