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In our combination therapy, Zn 2+ can not only suppress the generation of DHT in hair follicles, but also function as a specific activator of HHDPCs, which can effectively stimulate the transition of HHDPCs from the state of telogen to anagen and promote them to enter the growth phase by up-regulating the expression of some growth factorsIGF, PDGF, KGF, HGF, bFGF and C-Myc [44,69,75]

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In addition, in human alveolar epithelial cell, GHK-Cu significantly enhanced the expression of HO-1 which has been reduced by the stimulation of CSE

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Investigate whether disease progressing despite peptides requiring conventional treatment intensification

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