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doi: 10.1016/j.bbrc.2020.11.033

This blocks the combining of cysteine and glutamate before being joined with glycine to form more glutathione

DOI: Published: Publisher Name: Springer, Berlin, Heidelberg Print ISBN: 978-3-642-30017-2 Online ISBN: 978-3-642-30018-9 eBook Packages: Biomedical and Life SciencesReference Module Biomedical and Life Sciences

The use of redox-sensitive mbrB or mchlB and visualization of reduced glutathione via bright-field, fluorescence microscopy or CLSM, by contrast, allows insights into the in vivo situation within the nucleus and cytosol

The effectiveness of glutathione depends on its state within the cell

Pharmacol Rev 50:335356 Sipos K, Lange H, Fekete Z, Ullmann P, Lill R, Kispal G (2002) Maturation of cytosolic iron-sulfur proteins requires glutathione