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Therefore, new scoring methods that take into account MET staining in the cytoplasm, in addition to the plasma membrane, will enhance patient selection and subsequent outcomes

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The most frequent adverse events reported were nausea, constipation, fatigue, decreased appetite, injection site erythema, and injection site reaction, followed by vomiting, headache, diarrhea, dyspepsia, and nasopharyngitis (Table 3)

Moreover, Liu and colleagues treated 12-month-old APP/PS1 mice with MEM (5 mg/kg body weight) via intragastric administration and, they demonstrated that MEM treatment improved memory and learning impairment and significantly decreased A deposits in mice brains [45]

Bulletin of Experimental Biology and Medicine, 119 , 352-355