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When tumor volume reached about 50 mm 3 (volume=length x width 2 /2), mice were administered shRNA lentivirus (sh NC , negative control shRNA lentivirus

The purified recombinant TF-GT-1C324/347 S was incubated with the indicated concentrations of GSNO and then subjected to the TMT-switch assay

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Amish type microcephaly is a severe autosomal recessive metabolic disorder characterized by severe microcephaly apparent at birth, profoundly delayed psychomotor development, brain malformations, and episodic encephalopathy associated with lactic acidosis and -ketoglutaric aciduria (89)