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Among the several mAbs obtained, we initially focused on two mAbs, named M35 and M29, isolated from the spleens of two different mice, which recognized a single band of approximately 80 kDa in WB after SDS-PAGE of the SCMS ( Supplementary Figure S2A )

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Clinical pharmacology studies showed that taking oral semaglutide with food reduced its bioavailability by approximately 40-70% depending on the type and quantity of food consumed

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There were six groups, including one control group and five Fragment 176-191 groups