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Function and regulation of human copper-transporting ATPases

Bharath et al , 2002

Consequently, either extreme may upset the crucial redox balance needed for normal functional phenotypes in cells: too much or too little ROS will interfere with cell growth and survival

Moreover the hormonal rearrangement intrinsic of pregnancy [17] redistributes the interrelationships of metabolic pathways that sustain fetus growth and differentiation, particularly in rats, that have a short pregnancy (about 17 d)

For another, some immunosuppressive immune cells require GPX4 to forestall ferroptosis and maintain cell activation

Kowluru, R