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It contains a methyl group, which is necessary for a process known as methylation vital for many body functions, including detoxification, DNA repair, and the production of neurotransmitters

So people at greatest risk for deficiency include those with low stomach acid (e.g., older adults and people on proton pump inhibitors or antacids) or low IF production (known as pernicious anemia), people on medications that interfere with B12 absorption (such as metformin), people who have had gastric surgery, those with GI conditions that impair nutrient absorption (like celiac or Crohn's disease), and people on vegan and vegetarian diets

Mosa, R., Huang, L., Wu, Y., Fung, C., Mallawakankanamalage, O., LeRoith, D., & Chen, C

Neurologic aspects of cobalamin (B12) deficiency

We provide references to reputable sources on our website to aid in this process

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