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Moreover, previous studies have shown that Notch-dependent quiescent glioma cells are resistant to cytotoxic/anti-proliferative therapies (Eyler et al, 2020

These results indicate that the global transcriptomic profiles of the M and the C groups can be significantly distinguished, confirming that exogenous MT can disturb the global transcriptomic profile to enhance astaxanthin biosynthesis in P

This is also supported by our data showing that ENDO12 inhibits the secretion of IL-6 and IFN by primary splenic DCs in response to not only TLR9 but also TLR3 and TLR7 ligands

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Curcuminoids may interfere with the activity of efflux drug transporters of the ATP-binding cassette (ABC) family, including P-glycoprotein, multidrug resistance protein (MRP), and breast cancer-resistant protein (BCRP), which function as ATP-dependent efflux pumps that actively regulate the excretion of a number of drugs limiting their systemic bioavailability (116, 117)

To validate the stability of these findings in rice, we generated stably inherited transgenic rice lines expressing OsLIKE1 gene driven by three distinct promoters: the ubiquitin promoter (pUbi), the SNP type 1 promoter (pSNP type1 ), and the SNP type 2 promoter (pSNP type2 )