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doi: 10.1016/j.biopha.2023.115574 89 LoftusRMAssmannNKedia-MehtaNOBrienKLGarciaAGillespieCet al

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Furthermore, it has been reported that 4-hydroxynonenal (4-HNE), the most toxic type of aldehyde [13, 14] and H 2 O 2 [15, 16], have the ability to partake in signal transduction