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Positron emission tomography (PET) has identified lower GABAA receptor levels in the limbic system, including the nucleus accumbens, amygdala, and hippocampus, in high-functioning adult ASD patients compared to healthy controls (127)

Researchers have shown that a TFR-mediated increase in iron uptake in GCs induces the release of ROS, mitochondrial autophagy, and lipid peroxidation (108)