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[45] A case series reported benefit of 10% n-acetylcysteine cream applied to the back of 6 healthy volunteers who were exposed to dimethylsulfoxide

Similarly, animals with deficiencies in indirect scavengers of ROS, such as sulfiredoxin and metallothionein, are highly susceptible to alcohol-induced hepatic injury 27,31

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While vitamins exhibit potential in the biological mechanisms and treatment strategies for LLD (Figure 1), concerns regarding species differences, dose-dependent effects, and potential toxicity risks must be addressed

Glutathione is participating in leukotriene C4 (LTC4) synthesis, the primary cysteinyl leukotriene