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The AGE-RAGE signaling pathway The formation of AGEs also triggers activation of the receptor for AGEs (RAGE), which in turn exacerbates oxidative stress and inflammation through the stimulation of signaling pathways, such as NFB and NADPH oxidase, thereby sustaining a self-perpetuating cycle of vascular and tissue injury [24]

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Pre-culturing human adipose tissue mesenchymal stem cells under hypoxia increases their adipogenic and osteogenic differentiation potentials

DeLorenze GN, McCoy L, Tsai AL, Quesenberry CP Jr, Rice T, Il'yasova D, et al

Insert the spike aseptically into the bottle through the center target area of the rubber stopper

J Basic Microb 58(10):875882