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Zhang et al., 2003) permitting Na + influx, followed by cell depolarization and ATP release via CALHM1/3 channel (Taruno et al., 2013

Uritu, C

Lv L, Shi Y, Wu J, Li G (2021) Nanosized drug delivery systems for breast cancer stem cell targeting

Diverse Biological Activities The peptide's biological activities are remarkably diverse and include stimulation of collagen and glycosaminoglycan synthesis (critical for skin, connective tissue, and wound healing), activation of wound healing mechanisms, promotion of blood vessel formation (angiogenesis) to support tissue repair and regeneration, anti-inflammatory effects that resolve excessive inflammation while supporting beneficial healing responses, antioxidant and protective effects against oxidative damage and toxic compounds, attraction of immune and repair cells to sites of injury, remodeling of extracellular matrix through regulated metalloproteinase activity, stimulation of nerve outgrowth and regeneration, and even modulation of gene expression in patterns that reverse age-related changes and restore more youthful cellular function

Seow A, Quah SR, Nyam D, Straughan PT, Chua T, Aw TC: Food groups and the risk of colorectal carcinoma in an Asian population

This decline in the GHK-level coincides with the noticeable decrease in the regenerative capacity of the body