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The recommended dato-DXd dose is 6 mg/kg, with a maximum of 540 mg for patients with a weight of 90 kg or greater

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Pyridoxal phosphate (PLP) is integral to one-carbon metabolism, a series of biochemical reactions necessary for the synthesis of nucleotides and other molecules essential for DNA and RNA production (57, 58)

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This distinction matters significantly for how the body responds to treatment and the potential safety considerations involved