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4) Underexplored therapeutic strategies and model limitations: Preclinical studies have relied on in vitro mesangial cell models and lack validated animal models that fully recapitulate human IgA nephropathys pathological features (e.g., glomerular IgA1 deposition and mesangial proliferation)

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Smoking Experience before Adulthood Is Associated with an Increased Risk of Developing Ulcerative Colitis in Adult Ex-Smokers

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Thus, the oxidative by-products of ROS reaction pathways and of antioxidant concentrations are measured instead