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Measurements: colorimetric melanin dosing (absorbance 405-490 nm), tyrosinase activity by L-DOPA oxidation, MITF expression by qPCR, melanosomal translocation by microscopy

doi: 10.1093/gerona/glac135

It is also not always evident in the course of a chronic wound history when there is a need to reduce or stimulate ROS production, hence the importance of allying possible treatment strategies that target ROS with the use of sensors that could translate the actual needs of the wound at that given moment 193

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JS, AH, SW, and JG: review and editing