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A targeted metabolomic assay performed with uniformly labeled glutamine confirmed HuRs direct link to glutamine catabolism in the TCA cycle: decreased HuR levels decreased glutamine-derived glutamate, as well as citrate and malate, in both reductive and oxidative glutamine metabolic pathways

Luger, K., Rechsteiner, T

There is also a need to further understand the pathological role of autophagy-dependent GPX4 degradation in oxidative or reductive cell death [205]

Pakistan Journal of Biochemistry & Molecular Biology

While a protein-restricted diet reduces protein and amino acid intake to mitigate propionyl-CoA synthesis from propiogenic amino acids, fasting triggers broader metabolic alterations

Causes and metabolic consequences of fatty liver