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These findings underscore the importance of context, dosage regimen, and metabolic environment, reinforcing that the systemic benefits of lactate may be counteracted by localized biochemical disturbances in muscle tissue

Human forms of cytosolic SULTs and tissue distribution In the following text we will focus only on cytosolic sulfotransferases, since this enzyme superfamily plays a key role in the biotransformation of multiple xenobiotics as well as endogenous substrates