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Instead, raised levels may indicate: Liver disease (impaired B12 storage and release) Myeloproliferative disorders or certain leukaemias Renal impairment Recent B12 supplementation or injection Isolated high B12 is usually due to supplementation or binding-protein changes and should be assessed against clinical context and other tests

Food & Drug Administration (2022) Dietary supplements: What you need to know, National Institutes of Health (2023) Timing in drug absorption and disposition: The past, present, and future of chronopharmacokinetics, British Journal of Pharmacology (2020) Why is third-party certification important for dietary supplements?, Operation Supplement Safety (2024) Nursing fundamentals: Chapter 14, nutrition, National Library of Medicine (2021) Dietary supplements and bleeding, Baylor University Medical Center Proceedings (2022) Interactions between food and drugs, and nutritional status in renal patients: A narrative review, Nutrients (2022) Medically accurate: SingleCares Medical Review Board analyzes all of our content to confirm its in line with current medical advice
Pancreatic and liver disease may also occur
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