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Even if COPD is heterogenous in its manifestations, it usually includes two major pathologies: small airway disease with peribronchiolar fibrosis and emphysema with alveolar wall destruction [15]

This proof of principle is important as Cys111-targeted drug compounds could bind the free sulphydryl of both mutant or wild-type SOD1 and should not prevent structurally important hCCS-catalyzed activation

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prospective study with survival analysis in a consecutive series of 362 patients

Neuron 76(5):871885 Mahley RW, Innerarity TL, Rall SC Jr, Weisgraber KH (1984) Plasma lipoproteins: apolipoprotein structure and function

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