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These observations in part further allude to and acknowledge the complexity of mitochondrial function and its influence on biochemical pathways such as glucose handling by insulin-sensitive cells

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Contrary to the widespread assumption that psychedelics uniformly enhance cortical excitability, the evidence shows diverse, often opposing effects depending on dose, receptor localization, and neuronal compartment

[PMC free article: PMC2948179] [PubMed: 20398925] 222

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