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Oxidative damage to cells can lead to serious pathologies such as cancer, diabetes and cardiovascular disease

9.38k views 7 slides Glutathione Synthesis The Virtual Free Radical School

10.1038/s41419-021-03516-y 47 IshikawaC.SenbaM.MoriN

In summary, we highlight the importance of PSPH genetic alterations in GBM in promoting tumor aggressiveness and immunosuppression, which could be effectively targeted by a novel combinatorial therapeutic strategy of sertraline plus chloroquine