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Summary of evaluation 2.13

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For instance, patients may experience symptoms related to liver disease (such as jaundice, abdominal swelling, or fatigue), haematological disorders (including unexplained bruising, night sweats, or weight loss), or kidney dysfunction (such as reduced urine output or swelling)

They have a high affinity for inactive B12 analogues, although it is believed that this may also play a role in their elimination, as well as other functions that are still being studied and are largely unknown (including the transport of stored B12)

Calzada Ltd was aggressively pursuing this treatment route in the early 2010s, reporting in 2012 that AOD-9604 might promote cartilage creation and repair [in vitro] (Source)

[DOI] [PMC free article] [PubMed] [Google Scholar] 25 .Castelli MC, Friedman K, Sherry J, et al