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Although emerging evidence suggests that specific pathogens can colonise and exert pathological effects within the uterus, the mechanisms underlying maternal-fetal transmission and the downstream consequences for fetal health remain important directions for future investigation

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Nuclear translocation of FR is associated with increased proliferation and reprogramming toward a cancer stem cell through activation of numerous transcription factors, including OCT4/SOX2 (regulating stemness), KLF4 (regulating cell reprogramming), HES1 (regulating metastasis and multidrug resistance), and FGFR4 (regulating cellular proliferation)

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Dream assessment was also based on patient report without standardized instrumentsa reminder that this terrain remains to be mapped