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mansoni TGR was first cloned, we proposed that the enzyme was a selenoprotein with a penultimate Sec residue, and that TGR should have enzymatic activity dependent on the C-terminal Sec-containing motif in analogy to mammalian TrxR and TGR isoforms [11]

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Plant Physiol 97:863872 Fryer MJ, Ball L, Oxborough K, Karpinski S, Mullineaux PM, Baker NR (2003) Control of Ascorbate peroxidase 2 expression by hydrogen peroxide and leaf water status during excess light stress reveals a functional organisation of Arabidopsis leaves