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The response to treatment was heterogeneous and varied from no induction in patients with smaller GAA repeat expansions (280 and 580) to a 20%40% increase in frataxin protein after 4 weeks of treatment in patients with more than 800 GAA repeats (Figure 6, H and I)

Antioxidant additives using substances that delay or prevent the oxidation of cellular substrates have demonstrated the capacity to protect the human body against oxidative damage