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Kishton, M

GGCT affects the proliferation by disrupting the redox balance in tumor cells To explore the biological function of GGCT, we analyzed transcriptome data by knocking down GGCT in MHCC97H cells (GSE282603) and compared it with the published data from PC3 cells (GSE154584)

344 Notably, ATO administration can rescue a wide range of structural p53 mutants, including R175H, R175L, G245S, and R249S, but it cannot exert the same function in DNA contact mutants, such as R248Q and R273H