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For immunofluorescence, after deparaffinization, tissue sections were incubated with anti-rabbit ADA (1:400

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2023;41(2):304-322.e7

Stoichiometry Controls Activity of Phase-Separated Clusters of Actin Signaling Proteins

Cigarette smoke-induced oxidative stress and pro-inflammatory responses disrupt airway epithelial barrier function and lead to impaired gas exchange in the lungs, which promotes systemic hypoxia and induces intestinal hypoxia, inflammation, mucosal angiogenesis and epithelial cell death, as well as reduced intestinal barrier function, which leads to an increased risk of gastrointestinal disease (61, 62)