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The analyses of 4MSOB ITC and its conjugates were conducted using an Agilent HP1260 Series instrument coupled to an API5000 tandem mass spectrometer (AB Sciex, Darmstadt, Germany) by loading extracted samples onto an Agilent Zorbax Eclipse XDB-C18 column (50 4.6 mm 1.8 m, Agilent Technologies, Waldbronn, Germany) with mobile phase A (0.05% formic acid in milliQ water) and mobile phase B (acetonitrile)

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doi: 10.7554/eLife.63326 16 HeydtQLarrueCSalandEBertoliSSarryJEBessonAet al

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Dietary changes: B12 deficiency stems from dietary factors, like adhering to a strict vegan diet or experiencing malabsorption issues, integrating B12-rich foods into your diet proves beneficial

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The N-terminus and His-13 are crucial for Cu 2+ binding, and His-6 and His-14 are also implicated

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In the comparison between LPS and Control, cellular senescence and p53 signaling pathways, which are related to ferroptosis, were enriched in the top 20 of KEGG

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10.1002/bdd.2510110205 [DOI] [PubMed] [Google Scholar] Butterworth C

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