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Compared to the considerable knowledge concerning the intracellular metabolism of IBPs, little is known about the reprogramming of the host cell metabolism necessary for efficient intracellular IBP replication (Eisenreich et al., 2017)

Also, AC undergoes extensive metabolism, including oxidation, glucuronidation, sulfation, and methyl conjugation, yielding a wide range of metabolites

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Astrocyte-specific oxidative phosphorylation deficiency induces synaptic loss, neuroinflammation, demyelination, cognitive impairment, and metabolic and transcriptional signatures with significant overlap with mouse models of AD

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doi: 10.1016/j.chemphyslip.2008.09.004