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Hydration of dry areas

The cytotoxicity of apigenin nanoliposomes in colon cancer (HCT-15 and HT-29) cells is stronger than that of free apigenin [86]

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The GSH synthesis enhancer N-acetylcysteine (NAC) can restore the GSH level of PMN-MDSCs, but high doses may induce oxidative stress (182)

Remarkably, the low detection limit for GSH in the M to nM range was demonstrated by surface nanoarchitectured MOFs-centered biosensors

To address these challenges, strategies such as coadministration with piperine, lipid-based formulations, and nanoparticle microencapsulation have been developed