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Yap1 nuclear export is inhibited through diamide and hydroperoxides, which impair the connection between Yap1 and Crm1, resulting in Yap1 nuclear accumulation (So et al., 2019)

Rainey NE, Moustapha A, Saric A et al (2019) Iron chelation by curcumin suppresses both curcumin-induced autophagy and cell death together with iron overload neoplastic transformation

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Achieving this will require the development of unique orthogonal transformations to precisely functionalize proteins with diverse modifications

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