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Its ingenious design avoids the drawbacks of traditional oral and injection routes: The spray formulation enables MT-1 peptides to directly enter the bloodstream through the mucous membranes rich in capillaries in the mouth or nose, completely avoiding the degradation effect of enzymes in the gastrointestinal tract and the first-pass effect of the liver, thereby significantly improving bioavailability and achieving rapid onset within minutes

One real-world use and safety evaluation of Shenmai Injection showed that Shenmai Injection was mainly used for the adjuvant treatment of chemotherapy in cancer patients, among which BC was one of the most used tumors [40]

doi: 10.3389/fmed.2022.939776 108 SunBDingPSongYZhouJChenXPengCet al

For expressing DAF-16D/F::GFP fusion in the intestine (MCW441) we cloned GFP::unc-54 3 UTR without SL2 sequence to the 3position

PAGE: polyacrylamide gel electrophoresis

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