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10ln), further validating HR as the mechanism

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This review provides a comprehensive overview of ROS production in PCa, the interplay between androgens and ROS, the role of external factors such as obesity and aging in promoting ROS generation, and how elevated ROS levels alter the PCa microenvironment, promoting inflammation, activating the unfolded protein response (UPR), and regulating miRNA expression, all of which contribute to the progression of PCa

This depletion can lead to an increased risk of various health issues