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Due to a time lag in the conventional route of administration, there is a possibility that an active compound may become a slow-acting molecule that may be destroyed once it gets inside the brain tissue or enzyme catalytic activity rendering it useless [183]

doi:10.1016/j.jpha.2024.100976 462. Agarwal AK, Tunison K, Dalal JS, Yen CL, Farese RV Jr, Horton JD, Garg A

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most patients can be treated with another drug without incident

Ox-LDL also stimulates the release of monocyte-derived tumoral necrosis factor alpha (TNF-) and interleukin 1 beta (IL-1), leading to smooth muscle cell proliferation

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