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This effect is partly mediated through upregulation of anti-apoptotic proteins such as B-cell lymphoma 2 (Bcl-2), and downregulation of pro-apoptotic proteins such as tumour protein 53 and Bcl-2-associated X protein, collectively enhancing neuronal survival [50]

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RyszawyDPudeekMCatapanoJCiarachMSetkowiczZKondurackaEet alHigh doses of sodium ascorbate interfere with the expansion of glioblastoma multiforme cells in vitro and in vivo

GSK-3 is a regulator of several pathways such as inflammation, neuronal polarity, or either cell membrane signaling 72

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