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Thus, targeting Ca 2+ dysregulation observed in many muscular dystrophies might provide therapeutic benefits across a broad range of diseases, including dysferlinopathies (Burr & Molkentin, 2015)

This approach helps systematically analyze complex biological processes, such as the tumor microenvironment, thereby offering new insights for cancer drug development (Satija et al., 2015)

We found that GANP is a major regulator of gene expression in developing motor neurons, with GANP defects altering the expression of genes related to synaptic functions and resulting in compensatory induction of protein synthesis and mitochondrial pathways

Human hair follicle stem/progenitor cells express hypoxia markers

NAD+ therapy shows effects during or immediately after infusion for many patients

Pharmacological activators of Nrf2, including dimethyl fumarate and sulforaphane, mitigate oxidative stress and improve mitochondrial efficiency in preclinical disease models [252]